Diabetes Drugs List - Meglitinide

Meglitinide is a medicine in diabetes drugs list that works by stimulating the beta cells in the pancreas to produce insulin, stimulates insulin secretion. Active compounds of this class is repaglinide. These drugs modulate cell insulin production expenditures are one of them by triggering the release of insulin immediately after meals.

Which one of those meglitinide is repaglinide (Prandin), nateglinide (Starlix), and mitiglinida. Repaglinide is a benzoic acid derivative. This drug is a non-sulfonylurea meglitinide first introduced in 1998.

Meglitinide on Diabetes Drugs List
Meglitinide on Diabetes Drugs List

How Meglitinide Work?

Mechanisms of action and side effect profile similar to sulfonylurea repaglinide. This agent has a rapid onset and given time to eat, two to four times each day. Repaglinide can be as a substitute for patients who suffer from allergies to sulfa drugs are not recommended sulfonylurea. This medicine can be used as monotherapy or in combination with metformin. Should be given with caution in elderly patients and patients with impaired liver and kidney.

Nateglinide tend to work faster and shorter action than repaglinide. These drugs are particularly effective when combined with metformin or other diabetes drugs list. Another advantage, this drug is a good agent for patients who have kidney problems.

Common side effects are diarrhea and meglinitide type headache. Same with sulfnylurea, repaglinide have the risk of the heart. The newer types, such as nateglinide, has a similar but smaller risk.
Meglitinide has no direct effect on insulin eksitosis. Repaglinide has a very fast work, concentration and peak effect within 1 hour.

Repaglinide is indicated for the control of post-prandial glucose trip. Meglitinide should be used with caution in patients with impaired liver function.

Other medicine in diabetes drugs list in next article: Metformin